Hydrotalcite, layered double hydroxides (LDH), with hexagonal morphology has been rapidly synthesized by microwave reaction within 1 hour by urea hydrolysis from homogeneous solution. Different synthesis parameters, Mg/Al molar ratio, microwave reaction temperature and microwave power were systematically investigated. Pure hydrotalcite phase was obtained for Mg/Al ratios of 2:1 and 3:1, and higher reaction temperature gave higher crystallinity. The hydrotalcite synthesized at 600W power shows the highest crystallinity and more homogeneous crystal size distribution. The hydrotalcite samples were characterized by powder X-ray diffraction (XRD), simultaneous thermogravimetric/differential thermal analysis (TG/DTA), Fourier Transform Infrared (FT-IR) and Scanning electron micrograph (SEM).