Soil biofiltration is an environmentally-sound technology for elimination of VOCs, odorous and $NO_X$ compounds from a low concentration, high volume waste gas streams because of its simplicity and cost-effectiveness. This study investigated the optimal mixture fraction of briquet ash, compost, soil and loess for $NO_X$ degradation. Extreme vertices design was used to examine the role of four components on $NO_X$ degradation. Under our experimental conditions, 74.5% of $NO_X$ degradation was observed, using a model mixture(25% briquet ash, 10% compost, 30% soil and 40% loess) containing 100 ppb of NO. It was shown that experimental design analysis could allow selecting optimal conditions in such biodegradation processes in this study.