In this study, we conduct a case analysis on EZmedicom which is one of the leading companies in e-Marketplace for medical fields. By examining major business models of EZmedicom, we provide the success factors in launching the electronic commerce to the potential companies which are interested in participating in e-marketplace for medical fields. Especially, we deduct the solution, logistics field, and electronic group-purchasing as its major business model. Based on these factors, we also propose the MDvan solution which is one of the electronic purchase and supply system, Ezlogis that is the system supporting logistics parts in medical fields, VMI(vendor management inventory), standardization of item code and the linkage of SCM as its critical success factors of EZmedicom. The findings of this study suggest practical and managerial implications for e-Marketplace implementation in the medical field and further research.