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Fingerprinting Analysis of Fresh Ginseng Roots of Different Ages Using $^1H-NMR$ Spectroscopy and Principal Components Analysis
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  • Fingerprinting Analysis of Fresh Ginseng Roots of Different Ages Using $^1H-NMR$ Spectroscopy and Principal Components Analysis
  • Fingerprinting Analysis of Fresh Ginseng Roots of Different Ages Using $^1H-NMR$ Spectroscopy and Principal Components Analysis
저자명
Shin. Yoo-Soo,Bang. Kyong-Hwan,In. Dong-Soo,Kim. Ok-Tae,Hyun. Dong-Yoon,Ahn. In-Ok,Ku. Bon-Cho,Kim. Suk-Weon,Seong. Nak-Sul,Cha.
간행물명
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
권/호정보
2007년|30권 12호|pp.1625-1628 (4 pages)
발행정보
대한약학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Fingerprinting analysis of fresh ginseng according to root age was performed using $^1H-NMR$ spectroscopy and multivariate analysis techniques. Various peaks were detected in the aliphatic (0-3 ppm), sugar (3-6 ppm), and aromatic (6-9 ppm) regions of the $^1H-NMR$ spectra of the water extracts of fresh ginseng root. The use of principal components (PCs) analysis (PCA) for metabolomic profiling allowed the large $^1H-NMR$ data set obtained for various metabolites to be reduced to PC1, PC2, and PC3. Two dimensional score plots showed clear separations with these three components at different roots ages, and explained 89.6% of the total variance. Canonical discriminant analysis identified the ginseng roots at various ages from the NMR results with over 89.9% discrimination accuracy. These results indicate that the combination of $^1H-NMR$ and PCA provides a very promising tool for the authentication and quality control of fresh ginseng roots at different ages.