The purpose of this study is to examine how integrative art therapy affected the interaction of children with developmental disorder with their mothers from the viewpoint of object-relation theory that accentuated mother role for the promotion of mother-child interaction, and based on earlier studies on mother-child interaction and the interaction of children with developmental disorder with their mothers. The subjects in this study are five selected children and their mothers who used B and G social welfare agencies in Gyeonggi province. They are at the age of five and six in Western age, and have difficulties interacting with their parents. When a social maturity test is conducted, their social age ranged from 2.1 to 3.9, and as Portage Test is implemented, their developmental levels of sociability, cognition and language were identical to those of younger children who were at the age of one to 3.5. The major findings of the study are as follows. First, the children who suffered from developmental disorder and participated in this study showed a positive change in their interaction with their mothers. Second, as for connections between each session and mother-child interaction, most of them came to interact with their mothers better as the program came to an end.