This case study investigated the clinical effect of guided bone regeneration(GBR) using $Regenaform^{(R)};and;Ossix^{(R)}$ membrane and the histology of the new bone that formed just under the membranes. $Regenaform^{(R)}$ transplantation and covering with $Ossix^{(R)}$ membrane were performed to repair bone defects around implants after implantation in three patients. After $3{sim}4$ months, the membranes were removed in a second operation, and a biopsy was taken under the membrane. The biopsies showed a bone density of $23{sim}42%$, and subsequent prosthetic treatments were successful in all cases.