This study concerns the characteristics of helical flow in a concentric and eccentric annulus with a diameter ratio of 0.52 and 0.9, whose outer cylinders are stationary and inner ones are rotating. Pressure losses and skin friction coefficients have been measured for fully developed flows of water and 0.2% aqueous of sodium carboxymethyl cellulose (CMC), respectively, when the inner cylinder rotates at the speed of 0-500 rpm. The effect of rotation on the skin friction is significantly dependent on the flow regime. In all flow regimes, the skin friction coefficient is increased by the inner cylinder rotation. The change of skin friction coefficient corresponding to the variation of rotating speed is large for the laminar flow regime, whereas it becomes smaller as Re increases for the transitional flow regime and, then, it gradually approach to zero for the turbulent flow regime.