Objectives : The purpose of this study was to investigate the correlation of stress and meridian muscle electrography in Korean adult males. Methods : Sixty-nine volunteers suffering from stress participated in this study. Physical examination, stress survey and meridian muscle electrography were performed. Each variable was compared with each other by correlation analysis. Results : Correlation between stress response inventory and fatigue of trapezius muscle right upper portion was statistically significant. In relationship between sub scales of stress response inventory and meridian muscle electrography, fatigue of trapezius muscle right upper portion was statistically significant with tension, depression, and frustration. Contraction power of left sternocleidomastoid muscle was significant with somatization and others were not significant. Conclusions : In Korean adult males, trapezius muscle shows more fatigue under more stress. This suggests that stress influences muscle fatigue. Although meridian muscle electrography is not a typical method for the evaluation of pain nor stress, this is referential method to clinical evaluation of painful shoulder caused stress.