This paper describes the procedure and calculation results of basic design and transient variation of performance of 1 MWe large scale solar thermal power plant (STPP) by using the commercial software of THERMOFLEX and TRNSYS, respectively. In order to simulate the transient variation of STPP, the results of basic design are necessary. The design standard of the STPP is 1 MWe generation with solar only at high DNI condition and then 0.6 MWe output power for 1 hour using stored energy when the DNI becomes lower unable to operate normally. The results of basic design show the important design data of flow rates, water/steam conditions at each equipments and the estimated efficiency of STPP. In addition, dynamic simulation results of STPP are predicted and plotted for one year and three different days weather data of Daejeon.