In this paper, we suggest the high efficient control method based on general PI control law for a variable speed refrigeration system. In the variable speed refrigeration system, the capacity and the superheat are mainly controlled by an inverter and an electronic expansion valve, respectively, for saving energy and improving coefficient of performance. Thus, we proposed a decoupling model to eliminate the interfering loop between the capacity and superheat at first. Next, we designed PI controller to control the capacity and superheat independently and simultaneously. Finally, the control performance was investigated through some experiments. The experimental results showed that the proposed PI controller based on the decoupling model can obtain good control performance under the various control references and thermal load.