The aspheric lens has become the most popular optical component used in various optical devices such as digital cameras, pick-up lenses, printers, copiers etc. Using aspheric lenses not only miniaturizes and reduces the weight of products, but also lower prices and higher field angles can be realized. Additionally, plastic lenses are being changed to glass lenses more recently because of low accuracy, low acid-resistance and low thermal-resistance in the plastic lenses. Currently, one fabrication method of glass lenses is using a glass-mold method with a high precision mold core for mass production. In this paper, DOE (Design Of Experiments) and compensation machining were adopted to improve the surface roughness and the form accuracy of the mold core. The DOE has been done in order to discover the optimal grinding conditions which minimize the surface roughness with factors such as work spindle revolution, turbine spindle revolution, federate and cutting depth. And the compensation machining is used to generate high form accuracy of the mold core. From various experiments and analyses, we could obtain the best surface roughness 5 nm in Ra, form accuracy $0.167;{mu}m$ in PV.