This paper deals with the simulation model for A-Mart logistic center design and operations. In developed simulation model, receiving docks, conveyor sorter, conveyor system, shipping docks, material handling devices and manual sorting stations are considered. Three types of cargo such as transfer center cargo, distribution center cargo and supermarket cargo are considered. The simulation model and process animation are developed using the simulation package ARENA. Among various design and operation alternatives consisting of the number of workers of receiving dock, allocation of receiving docks by cargo types, conveyor sorter velocity, the number of folk-lift, the number of manual sorting operators and overall layout, the best alternatives of each subsystem are selected by simulation analysis. The major performance measures such as sorter throughput, utilization of operators at each station, receiving docks utilization and folk-lift utilization are considered for the alternative evaluation.