Purpose: The purpose of this study was to examine the effects of foot massage as a nursing intervention on the anxiety and pain of the mastectomy patients. Method: This research was quasi-experimental study of a total of 28 patients with 14 in the experimental group and 14 in the control group. For the experimental group, foot massage for 30 minutes was given by a foot-massage specialist. Anxiety and pain were measure once before the foot massage and five times after the massage. The collected data were analyzed by repeated ANOVA and t-test using the SPSS 12.0 program. Result: There was a statistically significant decrease in anxiety and pain in the experimental group compared to the control group over 5 different times. Conclusion: The foot massage was effective on anxiety and pain in mastectomy patients in this study. Therefore, foot massage would be usefully utilized as a nursing intervention for mastectomy patients.