This paper describes an evaluation method of pressure drop in a circular pipe of waste collection piping system. Accurate pressure drop in a piping system is very important to determine the capacity of turbo blower, which is one of the main elements in the system. Three-dimensional Navier-Stokes analysis is introduced to analyze the pressure drop in the piping system. Organic waste is selected and modeled using the result of site survey performed in an apartment area. Evaluation method of pressure drop used In the present numerical simulation is performed in the shortened pipe line prior to the calculation of the real system. Throughout the numerical simulation, pressure drop in a waste pipe is obtained and compared to the value determined by analytical method. The pressure drop obtained by numerical simulation has a good agreement with that of the analytic method. It is noted that present evaluation method is effective to determine a pressure drop in the piping system. Detailed flow characteristics inside the pipe line are also analyzed and discussed.