We here have found when the two parallel cylinders are arranged slightly non-coplanar, the vortex shedding could be significantly suppressed above Reynolds number of 6000. This finding is unlike the common understanding that the $K{acute{a}}rm{acute{a}}n$ vortex formation behind the structure can be manipulated when a structure located within the inherently unstable near wake of another structure. It is particularly important for flow control, since the flow-induced vibration of two parallel cylinders can be suppressed effectively with only slightly non-coplanar arrangement.