Purpose: This study investigated job stress and coping of ICU Nurses. Method: Data was accumulated from 206 ICU nurses serving at least more than one year in 500 bed order hospitals during the period of three months from June1, to August 30, 2006. Results: The average job stress was $2.96{pm}.95$ points, which was relatively high. The average coping was $2.55{pm}.23$ points. Conclusion: The extent of the job stress of ICU nurses was relatively high, and they received the heaviest stress from job circumstances. For the prevention of job stress, every effort is required to analyze the causes of stress caused by job circumstances and to pose an appropriate solution. Meanwhile, job stress, needs to be controlled using a solution for the central problem, and search for social support.