A relationship between the museum display wall composition and the visual spatial configuration is investigated in this study. From the previous research, existing types are classified in order to define the exhibition space of room to room. Based on the classification, an open room to room of art museum is defined as a room to room of museum, and the plane of museums is investigated. With the museums under this study, the wall of a room to room exhibition space as well as the visual spatial configuration are analyzed depending on the location of an opening, centering on the composition of unit space. In addition, two types of spatial composition are compared depending on the location of the opening. One type of spatial composition is lied on a straight line with visual continuity, and the visual line is found to be simple. Whereas, the other type has an invisible configuration between spaces due to a criss-crossed opening, so the space is perceived to be closed and disconnected. When comparing these two types, the advantage and disadvantage of each space are compared. As a result, a similar type and size of unit space are derived. In addition, the ratio of the opening compared to the total wall was found to be uniform, and a distribution of the opening and walls were found.