Postulation of flaws, one of the most important areas in RPV integrity assessment, significantly affects the results. In the present work, several parameters, such as orientation, underclad vs. surface cracking, crack depth and shape, etc., are postulated and parametric studies are performed to investigate the influence of the flaw parameters on the structural integrity assessment of the reactor pressure vessel during pressurized thermal shock. The influence of individual parameters describing the crack is evaluated based on sensitivity study results.