Objective : this study is designed to evaluate the effects of an oriental medicine therapy, namely gagam-sukhongjeon, on ulcerative colitis Methods : The Clinical data was analyzed on a patient with ulcerative colitis due to hanyeolchakjab(寒熱錯雜), whose symptoms were combined chillness and fever. The patient visited at the internal medicine department of Dong-Shin University Suncheon Oriental Hospital on February 25, 2006, and go into hospital from February 25, 2006 to March 9, 2006. and revisited from March 18, 2006 to April 5, 2006. The patient was treated with Herbal medicine(gagam-sukhongjeon) Result : After treatment, bloody stool and abdominal pain disappeared in visual analogue scale(VAS), pain disability index(PDI) and verbal rating scale(VRS). Conclusions : This study suggests that gagam-Sukhongjeon is significantly effective in treatment of ulcerative colitis.