This research examined use rate and profitability of equipment in hospital scale with about 500 beds to present data including to review before introducing PACS with the checklist included in preparation and proposal based on expected profit suggested by operation department and cost and use rate of the expensive medical equipment were analyzed. It was proved that profit was generated in the research subject hospital if PACS is introduced. Three to five year of lease is proper for the purchase method of medical equipment. Profit after two year of use will surpass investment cost and generate clear profit. Based on the profit generated from operation of radiology department, the purchase amount to introduce PACS at the hospital will be retrieved after about 1.9 years for the investment. The number of reshoot test at radiology department will be decreased and film, development, and fixer will not be necessary to buy so the operation cost will be reduced. Moreover, other than actual profit increased, the hospital can improve its reputation and employees can reduce their works and get better working environment with less stress. Their job satisfaction will be increased so they can improve service quality and it is good for marketing strategy of the hospital. As a result of this research, it was proved that the small and general hospital should have expected profit with introduction of PACS and analyze its contribution to treatment service and profit after the purchase. Then, the hospital should make a proposal for introduction of the medical equipment and establish effective operation plan.