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저자명
이정선,강문일,정용운,이채용,한동운,위성환,윤소라,조재진,강주원,Lee. Jung-Sun,Kang. Mun-Il,Chung. Yong-Un,Lee. Chai-Yong,Han. Dong-Un,Wee. Sung-Hwan,Yoon. S
간행물명
韓國家畜衛生學會誌
권/호정보
2008년|31권 4호|pp.533-546 (14 pages)
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한국가축위생학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

The efficacy of bovine immune sera to correct the calves with failure of passive transfer(FPT) was evaluated. Immune sera were produced from 14 one-year-old Holstein cattle which were inoculated commercial combined viral vaccine, administered by the challenge of some main enteric or respiratory viruses, aseptically filtered and stored at $4^{circ}C$ before used. After the treatment of bovine immune sera, Mean transfer factor($mg/d{ell}$, of IgG administered/kg of body weight) was $5.46{pm}2.74,;11.17{pm}1.27,;1.40{pm}0.21$ in K-IP, H-IP and K-IV group, respectively. The corrective effect of bovine immune sera to FPT calf without any clinical signs showed that intravenous route was more effective than intraperitoneal administration(P<0.01). FPT calves with severe signs were not effective response to the immunotherapy used and consequently died within 10 days after the treatment. Ten percentage of controls appeared the clinical signs including diarrhea. On the contrary, there were not any clinical signs in K-IP and H-IV group. There was significant increase of the neutralizing titer against bovine viral diarrhea virus and bovine coronavirus as well as of cell population including CD2, CD4, and monocyte in K-IP and H-IV group after the immunotherapy(P<0.05). Also, K-IP and H-IV group showed the successful correction to FPT within one week after the immunotherapy, but controls had kept the FPT two-four weeks even after the same treatment. Consequently, the results were suggesting that the bovine immune sera could be used the corrective tool to young calves with FPT.