Tubes in nuclear steam generators are held up by supports because the tubes are long and slender. Fluid flows of high-pressure and high-temperature in the tubes cause oscillating motions between tubes and supports. This is called as FIV (flow induced vibration), which causes fretting wear in contact parts of tube-support. The fretting wear of tube-support can threaten the safety of nuclear power plant. The tube and support materials were Inconel 690 and STS 409. The wear tests were conducted in various environments, which are in water without flow, in flowing water and in flowing water with air. The results showed that the flow of water influenced on the wear-life of tube. The wear-life of tube decreased in water flow as compared with wear-life in stationary water.