In this paper, robust structural design of the PEMFC stack gasket is pursued with Taguchi method by considering the noise factor in stack assembly. The study of noise problem in stacking is required to secure the safety and performance improvement of PEMFC stack. The design parameters in the Taguchi method are selected so that the structural responses are insensitive to the noise factors. In the gasket analysis, a Mooney-Rivlin strain energy function is used to consider hyperelasticity between load and displacement. By uni-axial and equi-biaxial tension tests of the gasket, the material properties are determined for the use in robust design of PEMFC gasket. The robust design of the PEMFC stack may provide structural reliability