The Kagome truss has been attracting attention, because it has equivalent or even higher strength compared to the octet truss with the same material and density. In this work, another aspect, which seems to be important for its practical applications, that is, defect sensitivity of bulk PCMs (periodic cellular metals) composed of Kagome trusses to mechanical behaviors subjected to compression was compared with a counterpart composed of octet trusses. In order to investigate the mechanical characteristics of bulk PCMs composed of the two trusses, a hybrid approach was taken in this work. First, assuming perfectly uniform structure and deformation of WBK, the behavior of the bulk PCMs composed of infinite number of trusses was simulated by finite element analysis for a unit cell with periodic boundary conditions. From the results, the force-displacement response of a single strut composing the trusses in each bulk PCM was estimated. Then, the effects of geometric imperfections and the inhomogeneous material properties were evaluated by network analyses, in which the force-displacement responses were used to characterize mechanical behaviors of the networks. The imperfections were modeled to have Gaussian distributions, and the analysis results of the two bulk PCMs were compared to evaluate their defect sensitivities. For the geometric imperfections, the maximum strength of both bulk PCMs decreased gradually as the imperfection level increased. For material property imperfections, the maximum strength maintained nearly unchanged for the PCM composed of Kagome trusses. On the other hand, for that composed of octet trusses, it slightly dropped as the imperfection level increased. The octet truss PCM was found to be more sensitive to the property imperfections than the other.