Purpose: This study was to evaluate and compare the effectiveness of the Resistance Exercise Program on pain, stiffness, ADL and bone mineral density in Arthritis Patients at home. Methods: Forty-two patients participated in this study and they were divided randomly into two groups (exercise and control group). Two subjects dropped during the study period. The exercise group had a structured training which was 50 minutes in duration, five times per week for a period of 16 weeks and the control group without any scheduled treatment. Data were gathered for 16 weeks (May 21, 2007- September 10, 2007) and were analyzed by using SPSS Win 12.0. Results: The pain, stiffness, ADL, balance and bone mineral density in the exercise group were improved significantly after the Resistance Exercise Program. However, a significant improvement on the above mentioned variables was not observed in the control group.