This paper presents the characteristics of mechanical properties within the heat affected zones(HAZs) of dissimilar metal weld joint between SA508 Gr.1a and F3l6 stainless steel(SS) with Alloy 82/182 filler metal. Tensile tests were performed using small-size specimens taken from the heat affected regions close to both fusion lines of weld, and the micro-structures were examined using optical microscope(OM) and transmission microscope(TEM). The results showed that significant gradients of the yield stress(YS), ultimate tensile stress(UTS), and elongations were observed within the HAZ of SA508 Gr.1a. This was attributed to the different microstructures within the HAZ developed during the welding process. In the HAZ of F316 SS, however, the welding effect dominated the YS and elongation rather than UTS. TEM micrographs demonstrated these characteristics of the HAZ of F316 SS was associated with a dislocation-induced strain hardening.