This paper presents a high efficiency half-bridge DC-DC converter for an LED backlight drive system of LCD module inspection equipment. The proposed converter improves the converter efficiency using characteristics of the asymmetrical half-bridge converter and the self-driven synchronous rectifier, and thus improves the total efficiency of the LED backlight drive system. The synchronous rectifier applied to the proposed converter is the new topological synchronous rectifier, which changes slightly the transformer structure and the synchronous switch connection in the asymmetrical half-bridge converter with a conventional self-driven synchronous rectifier. Since the proposed converter utilizes the transformer leakage inductor as its resonant inductor, its structure is simplified. The proposed converter well operates under the universal DC input voltage ($250{sim}380V$). The operational principle and a design example for a 100W prototype are discussed in detail, respectively. Experimental results are shown for the designed prototype converter under universal DC input voltage.