$DF_{21}$ diesel locomotive was designed to satisfy the requirement of Kunming Meter track and the 2Co self-guided radial bogie was used to suit the complex curve track. There are totally 12 locomotives was served on the track. The first two locomotives were devotion running on the track since April 2003, the wheel tread splling was occurred on the middle wheel set of the two locomotives after running nearly 150 thousands km on the track of the two locomotives at August 2004. The dynamic analysis was carried out to find the reason. The wheel set longitudinal vibration resonance phenomenon was existed on the locomotive dynamic performance, and this was caused by the too big longitudinal stiffness of the journal box bar on the middle wheel set. Wheel set longitudinal vibration resonance maybe an important reason of lead to wheel tread spalling. The corresponding mend methods were put forward from the point of view of wheel set longitudinal vibration resonance. All the wheel tread of the 12 locomotives on the middle wheel set were in good condition and not occurred the wheel tread spalling after the mend till December 2007 after 350 thousands km were finished. The mechanism of the wheel tread splling and corresponding mend method was discussed in detail in this paper.