The concept of lean production originated and was applied mainly to manufacture industries Even proven successful with such companies as Toyota, lean production has to be combined railway transportation production in order to bring its function into full play. The paper analyzes for applicability of lean production in railway transportation production organization, puts forward implementation methods such as transportation resource integration, station-zone organization, dispatch command optimization, railway performance evaluation index system, etc., and makes an exemplification study of lean production of Urumqi Railway Bureau in China, which testifies the applicability and efficiency of railway lean production.