A series of shaking table tests were conducted on a 1:12 scale model using scaled Taft N21E earthquake records to investigate the seismic performance of a 17-story high-rise reinforced concrete building structure with a high degree of torsional eccentricity and soft-story irregularities in the bottom two stories. The main characteristics of the behaviors were: (1) a sudden change of the predominant vibration mode from the mode of translation and torsion to the torsional mode after the flexible side underwent a substantial inelastic deformation; (2) an abrupt increase in the torsional stiffness during this change of modes; (3) a warping behavior of the wall in the torsional mode; and (4) a unilateral overturning moment in the transverse direction to the table excitations. In this study, efforts were made to simulate the above characteristics using a nonlinear analysis program, Perform3D. The advantages and limitations are presented with the nonlinear models available in this software, as they are related to the correlation between analysis and test results.