As a basic study for establishing a countermeasure for an oxygen deficient water mass (ODW), we investigated the variation of ODW volume according to the enforced total pollution load management in Jinhae Bay. This study estimated the inflowing pollutant loads into Jinhae Bay and predicted the reduction in ODW by using a sediment-water ecological model (SWEM). The result obtained in this study are summarized as follows: 1) The daily average pollutant loads of COD, SS, TN, TP, DIN, and DIP inflowing into Jinhae bay in 2005 were estimated to be about 12,218 kg-COD/day, 91,884 kg-SS/day, 5,292 kg-TN/day, 182 kg-TP/day, 4,236 kg-DIN/day, and 130 kg-DIP/day. 2) The calculated results of the tidal current by the hydrodynamic model showed good agreement with the observed currents. Also, an ecological model well reproduced the spatial distribution of the water quality in the bay. 3) This study defined the ODWDI (ODW decreasing index) in order to estimate the ODW decreasing volume caused by a reduction in the inflowing pollutant loads. As a result, the ODWDI was predicted to be about 0.91 (COD 30% reduction), 0.87 (COD 50% reduction), 0.79 (COD 70% reduction), 0.85 (ALL 30% reduction), 0.66 (ALL 50% reduction), and 0.45 (ALL 70% reduction). The ODW volume was decreased 1.5 $sim$ 2.6 times with a reduction in the COD, TN, and TP inflowing pollutant loads compared to a reduction in just the COD inflowing pollutant load. Therefore, it is necessary to enforce total pollution load management, not only for COD, but also fm TN and TP.