A quantitative model was developed in order to estimate fishery production damage due to anthropogenically induced environmental changes. The model is described in the following equation, $Y_D=frac{{phi}_D}{{phi}_G}[Y_0{cdot}(t_p-t_0)-frac{Y_0}{{phi}_G}(1-e^{-{phi}_G(t_p-t_0)})]$, where, $Y_D$ is annual amount of fishery production by nuclear power plant. ${varphi}$ D and ${varphi}$ G are instantaneous decreasing coefficient of fishery production by nuclear power plant and instantaneous decreasing coefficient of gross fishery production, respectively. $Y_0$ is annual mean fishery production without damages. $t_p$ is the present time, and $t_0$ is the starting time of damages. The model was applied to fishing grounds near a nuclear power plant on the east coast of Korea. Since fishery production damages have become bigger with increasing emission of thermal effluents from generators activities in the power plant, this factor has also been considered as, $delta_{D_i}=delta_D({sum}limits_{i=0}^{n};W_i/W_T)$, where, $delta_{Di}$ is the cumulative damage rate in fishery production from generators, $delta_D$ is the total cumulative damage rate in fishery production, $W_i$ is the emission amount of thermal effluents by generator i, and n is the number of generators in the nuclear power plant. This model can be used to conduct initial estimates of fishery production damages, before more detailed assessments are undertaken.