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Radiosurgical Considerations in the Treatment of Large Cerebral Arteriovenous Malformations
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  • Radiosurgical Considerations in the Treatment of Large Cerebral Arteriovenous Malformations
  • Radiosurgical Considerations in the Treatment of Large Cerebral Arteriovenous Malformations
저자명
Lee. Sung-Ho,Lim. Young-Jin,Choi. Seok-Keun,Kim. Tae-Sung,Rhee. Bong-Arm
간행물명
Journal of Korean neurosurgical society
권/호정보
2009년|46권 4호|pp.378-384 (7 pages)
발행정보
대한신경외과학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Objective : In order to establish the role of Gamma Knife radiosurgery (GKS) in large intracranial arteriovenous malformations (AVMs), we analyzed clinical characteristics, radiological features, and radiosurgical outcomes. Methods : Between March 1992 and March 2005, 28 of 33 patients with large AVMs (> $10;cm^3$ in nidus-volume) who were treated with GKS underwent single session radiosurgery (RS), and the other 5 patients underwent staged volumetric RS. Retrospectively collected data were available in 23 cases. We analyzed treatment outcomes in each subdivided groups and according to the AVM sizes. We compared the estimated volume, defined as primarily estimated nidus volume using MR images, with real target volume after excluding draining veins and feeding arteries embedded into the nidus. Results : Regarding those patients who underwent single session RS, 44.4% (8/18) had complete obliteration; regarding staged volumetric RS, the obliteration rate was 40% (2/5). The complete obliteration rate was 60% (6/10) in the smaller nidus group ($10-15;cm^3$ size), and 25% (2/8) in the larger nidus group (over $15;cm^3$ size). One case of cerebral edema and two cases (8.7%) of hemorrhage were seen during the latent period. The mean real target volume for 18 single sessions of RS was $17.1;cm^3$ ($10.1-38.4;cm^3$), in contrast with the mean estimated volume of $20.9;cm^3$ ($12.0-45.0;cm^3$). Conclusion : The radiosurgical treatment outcomes of large AVMs are generally poor. However, we presume that the recent development in planning software and imaging devices aid more accurate measurement of the nidus volume, therefore improving the treatment outcome.