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Continuous Production of Succinic Acid Using an External Membrane Cell Recycle System
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  • Continuous Production of Succinic Acid Using an External Membrane Cell Recycle System
  • Continuous Production of Succinic Acid Using an External Membrane Cell Recycle System
저자명
Kim. Moon-Il,Kim. Nag-Jong,Shang. Longan,Chang. Yong-Keun,Lee. Sang-Yup,Chang. Ho-Nam
간행물명
Journal of microbiology and biotechnology
권/호정보
2009년|19권 11호|pp.1369-1373 (5 pages)
발행정보
한국미생물생명공학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Succinic acid was produced by continuous fermentation of Actinobacillus succinogenes sp. 130Z in an external membrane cell recycle reactor to improve viable cell concentration and productivity. Using this system, cell concentration increased to 16.4 g/l at the dilution rate $0.2;h^{-1}$, up to 3 times higher than that of batch culture, and the volumetric productivity of succinic acid increased up to 6.63 g/l/h at the dilution rate $0.5;h^{-1}$, 5 times higher than that of batch fermentation. However, in the continuous culture using a high dilution rate, operational problems including severe membrane fouling and contamination by lactic acid producer were observed. Another succinic acid producer, Mannheimia succiniciproducens MBEL55E, was also utilized in this system, and the cell concentration and productivity of succinic acid at the dilution rate of $0.3;h^{-1}$ were found to be above 3 and 2.3 times higher, respectively, compared with those obtained at the dilution rate of $0.1;h^{-1}$. These observations give a deep insight into the process design for a continuous succinic acid production by microorganisms.