Purpose: The purpose of this study was to identify factors influencing on drinking refusal self-efficacy among university students. Method: The subjects consisted of 228 university students. The data were collected using self-reported questionnaires, which were constructed to include satisfaction of campus life and the DRSEQ-R(Drinking Refusal Self-Efficacy Questionnaire-Revised). Data were analyzed using the SPSS/PC WIN. 12.0 program. Results: The mean score indicating satisfaction of campus life was 3.20, and drinking refusal self-efficacy was 4.36. Satisfaction of campus life was positively correlated with drinking refusal self-efficacy. The gender, social circle, family history of drinking, drinking frequency, drinking quantity, and satisfaction of campus life explained 33.7% of the variance for drinking refusal self-efficacy. Conclusion: The findings suggest that satisfaction of campus life is an important factor for improving drinking refusal self-efficacy in university students. Therefore, strategies should be developed in order to promote drinking refusal self-efficacy and increase satisfaction of campus life in order to prevent drinking problems.