1. Objectives This study was designed to research the relationship between Sasang Constitution and Framingham coronary risk score(FRS), 2. Methods 666 people, over 40 years old, were participated in the community-based cohort in Wonju, South Korea from July 2nd to August 30th in 2006, Sasang Constitutional Diagnosis was carried out using PSSC(Phonetic System of Sasang Constitution), face and tongue photos and a checkup list, Framingham coronary risk score(FRS) was calculated using previously studied sheets adopted from KCDC(Korea Center for Disease Control and Prevention). 3. Results The average FRS of men was 7,06 and that of female was 8,19 which was significantly higher than that of men. There were significant differences between Taeeumin and other constitutions in women, whereas no differences among male constitutions. Analyzing adjusted ORs for CHD risk intervals according to Sasang constitution, they were 0.96 in Taeeumin and 1.70 in Soyangin to Soeumin. Also 0.55 in Taeeumin and 3.39 in Soyangin to Soeumin in men, 1.96 in Taeeumin and 1.87 in Soyangin to Soeumin in women. Women had highet FRS than men and female Taeeumin group have highet FRS points and CRP than other constitutions. 4. Conclusions Regarding the positive relationship between FRS, APG and CRP, it is thought to be useful to understand APG and CRP results at the same time when calculating FRS. When it comes to prevention and screening of CHD, female Taeeumin should be more careful and female Soyangin also should have a consideration of heart disease.