Objectives: The purpose of this study was to investigate self-rated health status and its influencing factors among low-income middle-aged women. Methods: Data on 594 women between the ages of 40 and 59 were collected from November 2007 to January 2008. Structured questionnaires were used to collect data. The following instruments-self efficacy, family support, health promotion behavior- were used in the study after some adaption. Results: The score for the health promotion behavior was 2.94(exercixe), 3.78(nutrition), 3.35(stress), 3.06(Health examination). The score for the self-efficacy was 3.47 and family support was 3.75. In the relationship between demographic and self-rated health status, there were significant differences in job, education level, self efficacy, family support, health promotion behavior. In hierarchy multiple regression analysis, the variables affecting the self-rated health status were job, education, exercise, health examination, family support, self efficacy. Conclusion: Self-efficacy and family support need to be considered in planning health program to improve self-rated health status among middle-aged women.