The fatigue resistance of twelve tubular textile samples designed for use in prototype endovascular devices was tested by an accelerated fatigue tester. Three time points were selected, namely 0, $26 imes10^6$, and $100 imes10^6$ cycles, which are equivalent to 0, 10 months, and 38.5 months implanted in the human body. Changes in tubular diameter, woven fabric count, thickness, mass per unit area, porosity, water permeability, and bursting strength were selected to characterize the performance of these samples before and after fatigue testing. The results showed that all the samples experienced some fatigue during the study, and the evidence of fatigue became more apparent with increasing time. There were clearly observable relationships between the textile parameters and the fatigue performance of the prototype samples. Woven construction, yarn size and yarn type all interacted with each other to influence the fatigue performance. Samples with twill weaves fatigued more readily than those with a 1/1 plain weave. For all three woven constructions, samples with larger yarn size fatigued more easily. However, the fatigue performance of some samples with multifilament weft yarns is severe.