This paper reports the installation of a carbon fiber ionizer in front of a fibrous medium filter to enhance the removal of submicron aerosol particles and bioaerosols. Test particles (KCl) were classified with a size range of 50-600 nm using a differential mobility analyzer (DMA). The number concentration of the test particles was measured using a condensation particle counter (CPC). The average charge per particle was estimated by current measurements using an aerosol electrometer. At the face velocity of 0.5 m/s, the particle removal efficiency was 31.4% (for dp=100 nm) when the ionizers were not operating but increased to 35.7% and 46.9% at $1.6{ imes}10^{11}ions/s$ and $6.4{ imes}10^{12}ions/s$ with the ionizers, respectively. For the antibacterial tests, the test bioaerosols (E. coli) were aerosolized using a nebulizer and were deposited on the filter media for 5 minutes. After the deposited bioaerosols were exposed to unipolar air ions, they were incubated for 12 hours. The survival efficiency of E. coli was measured using a colony counting method. The survival fractions of E. coli exposed to positive air ions for 1, 5 and 10 minutes were 61.7%, 45.4% and 25.2%, respectively.