In this study, flow-induced vibration(FIV) analyses have been conducted for a 3D compressor blade model. Advanced computational analysis system based on computational fluid dynamics(CFD) and computational structural dynamics(CSD) has been developed in order to investigate detailed dynamic responses of designed compressor blades. Fluid domains are modeled using the computational grid system with local grid deforming and remeshing techniques. Reynolds-averaged Navier-Stokes equations with $kappa-epsilon$ turbulence model are solved for unsteady flow problems of the rotating compressor model. A fully implicit time marching scheme based on the Newmark direct integration method is used for computing the coupled aeroelastic governing equations of the 3D compressor blade for fluid-structure interaction(FSI) problems. Detailed dynamic responses and instantaneous pressure contours on the blade surfaces considering flow-separation effects are presented to show the multi-physical phenomenon of the rotating compressor blade.