Hot-forging process and die design were made for a large-scale compressor wheel of Ti-6Al-4V alloy by using the results of 2-D FEM simulation. The design integrated the geometry-controlled approach and the processing contour map based on the dynamic materials model and the flow stability criteria. In order to obtain the processing contour map of Ti-6Al-4V alloy, compression tests were carried out in the temperature range of $915^{circ}C$ to $1015^{circ}C$ and the strain rate range of $10^{-3}s^{-1}$ to $10s^{-1}$. In the die design of the compressor wheel using the rigid-plastic FEM simulation, forging dimensional accuracy, the capacity of the forging machine and defect-free forging were considered as main design factors. The microstructure of hot forged wheel using the designed die showed a typical alpha-beta structure without forging-defects.