It is necessary to develop an efficient optimization technique to optimize engineering structures that have given design spaces, discrete design values, and several design goals. In this study, an optimum algorithm based on the genetic algorithm was applied to the multi-object problem to obtain an optimum solution that simultaneously minimizes the structural weight and construction cost of panel blocks in ship structures. The cost model was used in this study, which includes the cost of adjusting the weld-induced deformation and applying the deformation control methods, in addition to the cost of the material and the welding cost usually included in the normal cost model. By using the proposed cost model, more realistic optimum design results can be expected.