비파엽 열수추출물을 이용하여 항산화성과 항히스타민 및 항염증 효과를 조사하였다. 비파엽 열수추출물의 총 폴리페놀 함량은 28.91$pm$2.1 mg/g, 총 플라보노이드 함량은 10.54$pm$4.6 mg/g으로 분석되었다. 전자공여능은 400 $mu g$/mL 에서 81.04$pm$1.55%로 가장 높았으며, 아질산염 소거능은 pH 1.2($49.52pm1.04sim72.52pm$0.84%)> pH 4.2($35.28pm0.78sim51.20pm$1.10%)> pH 6.0($27.90pm0.36sim32.26pm$1.20%) 순으로 pH가 낮을수록 비파엽 열수추출물 농도가 높을수록 높았다. 비파엽 열수추출물 100, 200, 300 $mu g$/mL에서 $eta$-hexosaminidase 방출 억제능은 각각 14.58$pm$0.97%, 43.69$pm$0.96%, 95.58$pm$0.75%로 농도에 의존적으로 증가하였다. 비파엽 열수추출물을 이용하여 RAW cell을 대상으로 항염증 활성을 조사한 결과, 농도가 증가함에 따라 증가하여 400 $mu g$/mL에서 44.35$pm$0.63%를 나타내어 다양한 생리활성을 보여주었다.
This study was carried out to investigate physiological activities in the extract of Eriobotrya japonica in order to elevate its utilization as a functional material. The maximum total polyphenol and total flavonoid contents were 28.91$pm$2.1 mg/g and 10.54$pm$4.6 mg/g, respectively. The nitrite scavenging abilities at pH 1.2 were in the range of $49.52pm1.04sim72.52pm$0.84% whereas they were $35.28pm0.78sim51.20pm$1.10% at pH 4.2 and $27.90pm0.36sim32.26pm$1.20% at pH 6.0. At the concentrations of 100, 200 and 300 $mu g$/mL of the hot-water extract, the degranulation of RBL-2H3 cells were inhibited 14.58$pm$0.97%, 43.69$pm$0.96% and 95.58$pm$0.75%, respectively. The anti-inflammation activity was the highest as 44.35$pm$0.63% at a concentration of 400 $mu g$/mL.
