Recently, low birthrate has been recognized as a social problem, which is expressed as catastrophy of population. There are several reasons why low birth rate has occurred directly and indirectly, generating total economic and social burden for our society. That is, low birthrate should not be simply regarded as reduction of population. The present study identified the reasons of low birthrate and the current status of infertility, and examined practical and theoretical issues in terms of low birthrate. It is our contention that low birthrate and infertility is one of the most important governmental issue to enhance quality of life of the public. Thus, integrated and systematic policy must be developed and implemented to effectively meet the issues.