Objectives : The aim of this study was to show the rationale of point-selection on the methods of acupuncture and moxibustion in the Internal Injury section(in the Naegyeong chapter) of the Donguibogam. Methods : First, we summarized the cause of each disease in the Internal Injury section(in the Naegyeong chapter) of the Donguibogam. Then we explained the rationale of acupuncture point-selection referring to the cause of disease, physiology of the oriental medicine, other uses of each acupuncture points in the Donguibogam and other literature, character of each acupuncture points and specific acupuncture points etc. Results and Conclusions : Total 9 acupuncture points were used in the Internal Injury section(in the Naegyeong chapter) of the Donguibogam. Most of rationale of acupuncture point-selection were explained by specific acupuncture points, character of each acupuncture points, physiology of the oriental medicine and flow of meridian pathways etc. Each acupuncture points has practical application of specific diseases.