Objectives : The purpose of this case series was to investigate the effectiveness of Chengsimyeonjatang-gamibang for headache. Methods : The case subjects were nine patients who were diagnosed as Taeumin from the Department of Sasang Constitutional Medicine. They were selected among outpatients who visited Sangji Oriental Medical Hospital with complaint of headache from October 2007 to January 2008 through chart reviews. They were treated with Chengsimyeonjatang-gamibang without other treatments. Relative seriousness of headache was determined by Headache Impact $Test^{TM}$(HIT-$6^{TM}$) questionnaire. Results of before and after therapy were evaluated and scored using Visual Analogue Scale (VAS). The results were analyzed using statistical methods. such as Friedman test, Wilcoxon signed-rank test, and Mann-Whitney U Test. Results : The study showed that the VAS score significantly decreased after treatment (P<0.05). Conclusions : In summary, this case report suggests that Chengsimyeonjatang-gamibang appears to be effective in the treatment of headache.