Due to the increased water demand and severe drought as an effect of the global warming, the effluent from wastewater treatment plants becomes considered as an alternative water source to supply agricultural, industrial, and public (gardening) water demand. The effluent from the wastewater treatment plant is a sustainable water source because of its good quality and stable amount of water discharge. In this study, the water reuse system was developed to minimize total construction cost to cope with the uncertain water demand in future using two-stage stochastic linear programming with binary variables. The pipes in the water reuse network were constructed in two stages of which in the first stage, the water demands of users are assumed to be known, while the water demands in the second stage have uncertainty in the predicted value. However, the water reuse system has to be designed now when the future water demands are not known precisely. Therefore, the construction of a pipe parallel with the existing one was allowed to meet the increased water demands in the second stage. As a result, the trade-off of construction costs between a pipe with large diameter and two pipes having small diameters was evaluated and the optimal solution was found. Three scenarios for the future water demand were selected and a hypothetical water reuse network considering the uncertainties was optimized. The results provide the information about the economies of scale in the water reuse network and the long range water supply plan.