This study evaluates the seismic performance of reinforced concrete (RC) flat plate structures relation to the gravity shear ratio. For this purpose, 3 and 7 story framed buildings were designed for gravity loads only. Subsequently, a nonlinear static pushover analysis and a nonlinear time history analysis for the prototype buildings were carried out. In the nonlinear analysis, newly propose analytical slab-column joint model was utilized to capture punching shear failure and fracture mechanism in the analysis. The analytical results showed that seismic performance of RC flat plate frame is strongly influenced by the gravity shear ratio. In particularly, in the RC flat plate frame with a large gravity shear ratio the lateral strength and maximum drift capacity decreased significantly.