Design, Synthesis and Spectral Characterization of Novel 2-morpholino-N-(4,6-diarylpyrimidin-2-yl)acetamides

Design, Synthesis and Spectral Characterization of Novel 2-morpholino-N-(4,6-diarylpyrimidin-2-yl)acetamides
Design, Synthesis and Spectral Characterization of Novel 2-morpholino-N-(4,6-diarylpyrimidin-2-yl)acetamides

ㆍ 저자명: Kanagarajan. Vijayakumar,Thanusu. Jayaraman,Gopalakrishnan. Mannathusamy
ㆍ 간행물명: 대한화학회지
ㆍ 권/호정보: 2010년|54권 1호|pp.49-54 (6 pages)
ㆍ 발행정보: 대한화학회
ㆍ 파일정보: 정기간행물|ENG|
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ㆍ 주제분야: 기타

이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.

서지반출

영문초록

무수탄산칼륨 존재 하에서 2-chloro-N-(4,6-diarylpyrimidin-2-yl)acetamides 25-33를 모르포린과 축합 반응시켜서 2-morpholino-N-(4,6-diarylpyrimidin-2yl)acetamides 34-42 화합물들을 합성하였다. 합성된 화합물들의 녹는점, 원소분석, MS, FT-IR, $^1H$- & $^{13}C$-NMR로 화학적인 구조를 규명되었다.

기타언어초록

A new series of novel 2-morpholino-N-(4,6-diarylpyrimidin-2-yl)acetamides 34-42 is synthesized by the condensation of 2-chloro-N-(4,6-diarylpyrimidin-2-yl)acetamides 25-33 with morpholine in the presence of anhydrous potassium carbonate. The synthesized compounds have been characterized by melting point, elemental analysis, MS, FT-IR, one-dimensional NMR ($^1H$ & $^{13}C$) spectroscopic data.

키워드

모르포린 클로로아세틸화반응 2-Morpholino-N-(4 6-diarylpyrimidin-2-yl)acetamides 4 6-Diarylpyrimidin-2-amines Chloroacetylation Morpholine Synthesis

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