CQUEAN (Camera for QUasars in EArly uNiverse) is an optical CCD camera system that consists of a science CCD camera, a guide CCD camera, and seven filters. In addition, a focal reducer is installed in front of the science camera to secure a larger field of view for the system. Engineering run of the system was carried out from Aug. 10, 2010 to Aug. 17, 2010, with 2.1m Otto Struve telescope at McDonald Observatory, USA, from which we investigated the characteristics and performance of the system. Bias and dark images were taken under various temperature conditions to examine the system behavior, and both twilight and dome flat images were obtained to investigate the appropriate preprocessing procedures of the data. Crude initial estimate indicated one hour integration would reach limiting magnitude of 24.2 in i-band with S/N ratio of 5, with CQUEAN at 2.1m telescope. The detailed results of the engineering run will be presented.